![]() Similarly, Stone et al showed that pre-percutaneous coronary intervention (pre-PCI) TIMI flow grade 3 (pre-TIMI 3) was an independent predictor of survival in patients with ST-segment elevation myocardial infarction (STEMI). In the harmonizing outcomes with revascularization and stents in acute myocardial infarction (HORIZONS-AMI) trial, the presence of early IRA patency, defined as thrombolysis in myocardial infarction (TIMI) flow grade 2/3, was associated with lower rates of 1-year mortality (2.5% vs 3.9%, P =. The presence or absence of reperfusion of an infarct-related artery (IRA) is a major determinant of prognosis in patients with acute myocardial infarction (AMI). However, the cumulative incidences of recurrent myocardial infarction, any revascularization, and ST were similar between the 2 groups.Īmong a contemporary cohort of NSTEMI, these data suggest that the presence of a pre-PCI patency of the infarct-related artery showed better mortality reduction capacity than those with a lack of patency. Moreover, these differences were more prominent during the first 1 month after the index PCI. 001) rates were significantly higher in the pre-TIMI 0/1 group than in the pre-TIMI 2/3 group. Major adverse cardiac events (hazard ration, 1.294 95% confidence interval : 1.065–1.572 P =. The secondary outcome was stent thrombosis (ST).Īfter propensity score-matched (PSM) analysis, 2 PSM groups (2473 pairs, n = 4946, C-statistic = 0.684) were generated. The primary outcome was major adverse cardiac events defined as all-cause death, recurrent myocardial infarction, or any repeat revascularization. īecause of a paucity of published data, we compared the 2-year major clinical outcomes between pre-percutaneous coronary intervention (pre-PCI) thrombolysis in myocardial infarction (TIMI) flow grade 0/1 (pre-TIMI flow grade 0/1) group and pre-PCI TIMI flow grade 2/3 (pre-TIMI 2/3) group in patients with non-ST-segment elevation myocardial infarction (NSTEMI) who underwent successful implantation of newer-generation drug-eluting stent.Ī total of 7506 NSTEMI patients were divided into 2 groups: pre-TIMI 0/1 group (n = 3157) and pre-TIMI 2/3 group (n = 4349). The work cannot be used commercially without permission from the journal. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Website ( This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. Supplemental digital content is available for this article. The authors have no conflicts of interest to disclose.Īll data generated or analyzed during this study are included in this published article. This research was supported by a fund (2016-ER6304-02) by Research of Korea Centers for Disease Control and Prevention. ![]() YHK and A-YH contributed equally to this work. Association of pre-percutaneous coronary flow grade and clinical outcomes in patients with non-ST-segment elevation myocardial infarction: Data from the Korea Acute Myocardial Infarction Registry. How to cite this article: Kim YH, Her AY, Jeong MH, Kim BK, Hong SJ, Kim S, Ahn CM, Kim JS, Ko YG, Choi D, Hong MK, Jang Y. ![]() ∗Correspondence: Yong Hoon Kim, Division of Cardiology, Department of Internal Medicine, Kangwon National University School of Medicine 24289, 156 Baengnyeong Road, Chuncheon City, Gangwon Province, Republic of Korea (e-mail: ),Ībbreviations: DES = drug-eluting stent, KAMIR = Korea Acute Myocardial Infarction Registry, MACEs = major adverse cardiac events, NSTEMI = non-ST-elevation myocardial infarction, PCI = percutaneous coronary intervention, Pre-TIMI = pre-TIMI flow grade, Re-MI = recurrent myocardial infarction, ST = stent thrombosis, TIMI = thrombolysis in myocardial infarction. ADivision of Cardiology, Department of Internal Medicine, Kangwon National University School of Medicine, Chuncheon, Republic of KoreaīCardiovascular Center, Department of Cardiology, Chonnam National University Hospital, Gwangju, Republic of KoreaĬDivision of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Republic of KoreaĭDivision of Cardiology, Inje University College of Medicine, Haeundae Paik Hospital, Busan, Republic of Korea. ![]()
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